Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.B3 extracted from

  • Pemberton, A.D.; Zamolodchikova, T.S.; Scudamore, C.L.; Chilvers, E.R.; Miller, H.R.; Walker, T.R.
    Proteolytic action of duodenase is required to induce DNA synthesis in pulmonary artery fibroblasts (2002), Eur. J. Biochem., 269, 1171-1180.
    View publication on PubMed
Search for more literature for 3.4.21.B3

Inhibitors

Inhibitors Comment Organism Structure
Trypsin inhibitor from soybean Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polypeptide + H2O Bos taurus
-
 peptides
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus P80219
-
-

Purification (Commentary)

Purification (Comment) Organism
at least 90% purity Bos taurus

Reaction

Reaction Comment Organism Reaction ID
proteolytic cleavage of polypeptides to large and stable peptides, preferential cleavage sites: Lys-, Arg-, Tyr-, Phe-, Leu-, -Pro serine protease which has a dual specificity, i.e. both trypsin-like and chymotrypsin-like activities Bos taurus
a

Source Tissue

Source Tissue Comment Organism Textmining
epithelium
-
 Bos taurus
-
fibroblast from pulmonary artery Bos taurus
-
jejunum intestinal mucosa Bos taurus
-
lamina propria
-
 Bos taurus
-
lung around brochioles and within alveolar septa Bos taurus
-
mast cell spindle or stellate-shaped, located pricipally in the lamina propria and submucosa Bos taurus
-
mucosa
-
 Bos taurus
-
pulmonary artery endothelial cell fibroblast Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
polypeptide + H2O
-
 Bos taurus peptides
-
 ?

Synonyms

Synonyms Comment Organism
duodenase I
-
 Bos taurus
duodenase serine protease
-
 Bos taurus