Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.B3 extracted from

  • Zamolodchikova T.S.; Vorotyntseva T.I.; Nazimov I.V.; Grishina G.A.
    Duodenase, a new serine protease of unusual specificity from bovine duodenal mucosa. Primary structure of the enzyme (1995), Eur. J. Biochem., 227, 873-879.
    View publication on PubMed
Search for more literature for 3.4.21.B3

Inhibitors

Inhibitors Comment Organism Structure
phenylmethanesulfonyl fluoride
-
 Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
29060
-
 amino acid sequence determination, without sugar chain Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polypeptide + H2O Bos taurus enzyme belongs to the serine protease subfamily peptides
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus P80219
-
-

Source Tissue

Source Tissue Comment Organism Textmining
duodenum
-
 Bos taurus
-
mucosa
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
polypeptide + H2O enzyme belongs to the serine protease subfamily Bos taurus peptides
-
 ?
polypeptide + H2O enzyme shows very broad substrate specificity due to absence of the SH-bridge at residues 191 and 220, chymotrypsinogen numbering, with retention of normal catalytic activity compared to other serine proteases, similar to granzyme-like proteases Bos taurus peptides
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 29060, amino acid sequence determination, without sugar chain Bos taurus

Synonyms

Synonyms Comment Organism
duodenase I
-
 Bos taurus
duodenase serine protease
-
 Bos taurus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
-
 Bos taurus

pI Value

Organism Comment pI Value Maximum pI Value
Bos taurus
-
-
 10