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Literature summary for 3.4.21.B27 extracted from

  • Senturker, S.; Thomas, J.T.; Mateshaytis, J.; Moos, M.
    A homolog of subtilisin-like proprotein convertase 7 is essential to anterior neural development in Xenopus (2012), PLoS ONE, 7, e39380.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.B27

Cloned(Commentary)

Cloned (Comment) Organism
gene SPC7, DNA and amino acid sequence determination and analysis Xenopus laevis

Organism

Organism UniProt Comment Textmining
Xenopus laevis E1U2Y7 gene SPC7
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Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Xenopus laevis
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embryo expression of gene SPC7 mRNA in Xenopus laevis embryos at different developmental stages by real-time PCR expression analysis, overview Xenopus laevis
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eye
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 Xenopus laevis
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Synonyms

Synonyms Comment Organism
SPC7
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 Xenopus laevis
subtilisin-like proprotein convertase 7
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 Xenopus laevis

General Information

General Information Comment Organism
evolution the enzyme is a member of the subtilisin/kexin family of pro-protein convertases Xenopus laevis
malfunction enzyme loss of function suppresses markers for anterior patterning of neural tissues and early eye development Xenopus laevis
physiological function the enzyme cleaves many pro-proteins to release their active proteins, including members of the bone morphogenetic protein (BMP) family of signaling molecules. The enzyme is required during embryonic development of eyes and brain, overview Xenopus laevis