Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.B27 extracted from

  • Rousselet, E.; Benjannet, S.; Hamelin, J.; Canuel, M.; Seidah, N.
    The proprotein convertase PC7: Unique zymogen activation and trafficking pathways (2011), J. Biol. Chem., 286, 2728-2738.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.B27

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293 and COS-1 cells Homo sapiens
expressed in HEK-293 and COS-1 cells Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum proenzyme Homo sapiens 5783
-
endoplasmic reticulum proenzyme Rattus norvegicus 5783
-
membrane active enzyme, proprotein convertase reaches the cell surface by a non-conventional secretory pathway through a brefeldin A- and COPII-coated vesicles independent way Homo sapiens 16020
-
membrane active enzyme, proprotein convertase reaches the cell surface by a non-conventional secretory pathway through a brefeldin A- and COPII-coated vesicles independent way Rattus norvegicus 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
85000
-
 x * 85000, SDS-PAGE Homo sapiens
85000
-
 x * 85000, SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein mature proprotein convertase 7 is partially sulfated, Cys699 and Cys704 are palmitoylated at its cytosolic tail. The enzyme also undergoes N-glycosylation Homo sapiens
glycoprotein mature proprotein convertase 7 is partially sulfated, Cys699 and Cys704 are palmitoylated at its cytosolic tail. The enzyme also undergoes N-glycosylation Rattus norvegicus

Subunits

Subunits Comment Organism
? x * 85000, SDS-PAGE Homo sapiens
? x * 85000, SDS-PAGE Rattus norvegicus

Synonyms

Synonyms Comment Organism
PC7
-
 Homo sapiens
PC7
-
 Rattus norvegicus