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Literature summary for 3.4.21.B26 extracted from

  • Basak, A.; Zhong, M.; Munzer, J.S.; Chretien, M.; Seidah, N.G.
    Implication of the proprotein convertases furin, PC5 and PC7 in the cleavage of surface glycoproteins of Hong Kong, Ebola and respiratory syncytial viruses: a comparative analysis with fluorogenic peptides (2001), Biochem. J., 353, 537-545.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.B26

Inhibitors

Inhibitors Comment Organism Structure
14-dehydroandrographolide succinoyl monoester syn: SEA, 0.25 mM Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0021
-
 2-aminobenzoyl-RNTPRERKKRGL-(3-nitro)-Tyr-A pH 7, 37°C Mus musculus
0.0031
-
 2-aminobenzoyl-SKKRKRRFLG-(3-nitro)-Tyr-A pH 7, 37°C Mus musculus
0.0031
-
 2-aminobenzoyl-GGRRTRREAI-(3-nitro)-Tyr-A pH 7, 37°C Mus musculus
0.0033
-
 2-aminobenzoyl-RNTPRRRKKRGL-(3-nitro)-Tyr-A pH 7, 37°C Mus musculus
0.0042
-
 2-aminobenzoyl-RNTPRKKRGL-(3-nitro)-Tyr-A pH 7, 37°C Mus musculus
0.0051
-
 2-aminobenzoyl-RNTPRERRRKKRGL-(3-nitro)-Tyr-A pH 7, 37°C Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-aminobenzoic acid-SKKRKRRFLG-(3-nitro)-Tyr-A + H2O fluorogenic substrate encompassing the processing site of envelope glycoproteins of respiratory syncytial virus Mus musculus 2-aminobenzoic acid-SKKRKRR + FLG-(3-nitro)-Tyr-A
-
 ?
2-aminobenzoyl-GGRRTRREAI-(3-nitro)-Tyr-A + H2O fluorogenic substrate encompassing the processing site of envelope glycoproteins of ebola virus Mus musculus 2-aminobenzoyl-GGRRTRR + EAI-(3-nitro)-Tyr-A
-
 ?
2-aminobenzoyl-RNTPRERKKRGL-(3-nitro)-Tyr-A + H2O
-
 Mus musculus 2-aminobenzoyl-RNTPRERKKR + GL-(3-nitro)-Tyr-A
-
 ?
2-aminobenzoyl-RNTPRERRRKKRGL-(3-nitro)-Tyr-A + H2O fluorogenic substrate encompassing the processing site of envelope glycoproteins of Hong Kong virus Mus musculus 2-aminobenzoyl-RNTPRERRRKKR + GL-(3-nitro)-Tyr-A
-
 ?
2-aminobenzoyl-RNTPRKKRGL-(3-nitro)-Tyr-A + H2O
-
 Mus musculus 2-aminobenzoyl-RNTPRKKR + GL-(3-nitro)-Tyr-A
-
 ?
2-aminobenzoyl-RNTPRRRKKRGL-(3-nitro)-Tyr-A + H2O
-
 Mus musculus 2-aminobenzoyl-RNTPRRRKKR + GL-(3-nitro)-Tyr-A
-
 ?
2-aminobenzoyl-SKKRKRRFLG-(3-nitro)-Tyr-A + H2O
-
 Mus musculus 2-aminobenzoyl-SKKRKRR + FLG-(3-nitro)-Tyr-A
-
 ?

Synonyms

Synonyms Comment Organism
PC5
-
 Mus musculus