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Literature summary for 3.4.21.B21 extracted from

  • Bamford, C.V.; Fenno, J.C.; Jenkinson, H.F.; Dymock, D.
    The chymotrypsin-like protease complex of Treponema denticola ATCC 35405 mediates fibrinogen adherence and degradation (2007), Infect. Immun., 75, 4364-4372.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.B21

Protein Variants

Protein Variants Comment Organism
additional information in the isogenic CTLP mutant strain, CKE, chymotrypsin-like activity is reduced more than 90% compared to that in the wild type and fibrinogen binding and hydrolysis are ablated, the isogenic mutant strain MHE shows levels of CTLP reduced 40% relative to those in the wild type and exhibits correspondingly reduced levels of fibrinogen binding and proteolysis Treponema denticola

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
100000
-
 SDS-PAGE Treponema denticola

Organism

Organism UniProt Comment Textmining
Treponema denticola P96091 strain ATCC 35405
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fibrinogen + H2O
-
 Treponema denticola ?
-
 ?

Synonyms

Synonyms Comment Organism
chymotrypsin-like protease
-
 Treponema denticola
CTLP
-
 Treponema denticola
dentilisin
-
 Treponema denticola

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
100
-
 heating at 100°C abolishes enzyme activity Treponema denticola