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Literature summary for 3.4.21.B21 extracted from

  • Miyamoto, M.; Ishihara, K.; Okuda, K.
    The Treponema denticola surface protease dentilisin degrades interleukin-1 beta (IL-1 beta), IL-6, and tumor necrosis factor alpha (2006), Infect. Immun., 74, 2462-2467.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine Treponema denticola exerts a pathogenic effect on periodontal tissue via local dysregulation of inflammatory cytokines by dentilisin Treponema denticola

Protein Variants

Protein Variants Comment Organism
additional information dentilisin-deficient mutant K1 Treponema denticola

Organism

Organism UniProt Comment Textmining
Treponema denticola
-
strain ATCC 35405
-
Treponema denticola P96091 strain ATCC 35405
-

Purification (Commentary)

Purification (Comment) Organism
-
Treponema denticola

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
interleukin-1 beta + H2O
-
Treponema denticola ?
-
?
interleukin-1beta + H2O
-
Treponema denticola ?
-
?
interleukin-6 + H2O
-
Treponema denticola ?
-
?
tumor necrosis factor alpha + H2O
-
Treponema denticola ?
-
?

Synonyms

Synonyms Comment Organism
dentilisin
-
Treponema denticola