Literature summary for 3.4.21.B2 extracted from

Wu, L.; Wang, L.; Hua, G.; Liu, K.; Yang, X.; Zhai, Y.; Bartlam, M.; Sun, F.; Fan, Z.
Structural basis for proteolytic specificity of the human apoptosis-inducing granzyme M (2009), J. Immunol., 183, 421-429.

Search for more literature for 3.4.21.B2

Crystallization (Commentary)

Crystallization (Comment)	Organism
crystal structures of wild-type hGzmM, the inactive D86N-GzmM mutant with bound peptide substrate, and the complexes with a catalytic product and with a tetrapeptide chloromethylketone inhibitor are solved to 1.96 A, 2.30 A, 2.17 A and 2.70 A, respectively	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
D86N	inactive mutant enzyme	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P51124	-	-

Synonyms

Synonyms	Comment	Organism
GZmM	-	Homo sapiens
hGzmM	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)