Activating Compound | Comment | Organism | Structure |
---|---|---|---|
androgens | up-regulation of gene expression | Homo sapiens | |
progestins | up-regulation of gene expression in breast carcinoma | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | enzyme might be useful as diagnostic marker in ovarian cancer | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | enzyme is regulated by steroid hormones, contains androgen response elements in the proximal promotor region | ? | - |
? | |
polypeptide + H2O | Homo sapiens | - |
peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y5K2 | - |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
proteolysis of polypeptides | substrate binding pocket contains an Asp residue | Homo sapiens | |
proteolysis of polypeptides | enzyme is a serine protease | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
BT-474 cell | breast carcinoma cell line, enzyme is upregulated by progetsins and androgens | Homo sapiens | - |
cell culture | breast carcinoma cell line | Homo sapiens | - |
LNCaP cell | prostate carcinoma cell line, enzyme is upregulated by androgens | Homo sapiens | - |
ovarian carcinoma cell | gene overexpression | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme is regulated by steroid hormones, contains androgen response elements in the proximal promotor region | Homo sapiens | ? | - |
? | |
polypeptide + H2O | - |
Homo sapiens | peptides | - |
? |
Synonyms | Comment | Organism |
---|---|---|
EMSP1 | - |
Homo sapiens |
K4 | - |
Homo sapiens |
PRSS17 | - |
Homo sapiens |