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Literature summary for 3.4.21.B10 extracted from

  • Debela, M.; Magdolen, V.; Schechter, N.; Valachova, M.; Lottspeich, F.; Craik, C.S.; Choe, Y.; Bode, W.; Goettig, P.
    Specificity profiling of seven human tissue kallikreins reveals individual subsite preferences (2006), J. Biol. Chem., 281, 25678-25688.
    View publication on PubMed
Search for more literature for 3.4.21.B10

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli M15(pREP4) cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q92876 precursor
-

Purification (Commentary)

Purification (Comment) Organism
nickel-nitrilotriacetic acid-Sepharose column chromatography and benzamidine-Sepharose column chromatography Homo sapiens

Renatured (Commentary)

Renatured (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
kidney
-
 Homo sapiens
-
pancreas
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-FR-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens benzyloxycarbonyl-FR + 7-amino-4-methylcoumarin
-
 ?
benzyloxycarbonyl-LR-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens benzyloxycarbonyl-LR + 7-amino-4-methylcoumarin
-
 ?
additional information strong preference for P1-Arg over Lys, which is accepted nearly equally as well as Ala, Met, and Nle Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
hK6 displays a trypsin-like specificity with strong preference for P1-Arg Homo sapiens
myelencephalonspecific protease
-
 Homo sapiens
neurosin
-
 Homo sapiens
protease M
-
 Homo sapiens