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Literature summary for 3.4.21.B1 extracted from

  • Yamamoto, E.; Nishimura, N.; Okada, K.; Sekido, C.; Yamamichi, S.; Hasumi, K.
    Inhibitors of autoactivation of plasma hyaluronan-binding protein (factor VII activating protease) (2011), Biol. Pharm. Bull., 34, 462-470.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
factor VII + H2O
-
Homo sapiens activated factor VII + ?
-
?
additional information pro-plasma hyaluronan-binding protein autoproteolytically converts to an active two-chain form with the aid of an effector such as spermidine and heparin. Tannic acid, delphinidin, hamamelitannin, (-)-epicatechin gallate, and 3,5-di-O-caffeoylquinic inhibit spermidine-induced pro-plasma hyaluronan-binding protein autoactivation Homo sapiens ?
-
?
prourokinase + H2O
-
Homo sapiens urokinase + ?
-
?
Spectrozyme TH + H2O
-
Homo sapiens ? + 4-nitroaniline
-
?

Synonyms

Synonyms Comment Organism
factor VII activating protease
-
Homo sapiens
PHBP
-
Homo sapiens
plasma hyaluronan-binding protein
-
Homo sapiens

General Information

General Information Comment Organism
physiological function the enzyme plays roles in regulating inflammation, vascular function, fibrosis and atherosclerosis Homo sapiens