Protein Variants | Comment | Organism |
---|---|---|
T54A | the mutation is associated with low to medium levels of resistance to the HCV NS3-4A serine protease inhibitor telaprevir (VX-950) | Hepacivirus C |
T54S | the mutation is associated with low to medium levels of resistance to the HCV NS3-4A serine protease inhibitor telaprevir (VX-950) | Hepacivirus C |
V36A | the mutation is associated with low to medium levels of resistance to the HCV NS3-4A serine protease inhibitor telaprevir (VX-950) | Hepacivirus C |
V36G | the mutation is associated with low to medium levels of resistance to the HCV NS3-4A serine protease inhibitor telaprevir (VX-950) | Hepacivirus C |
V36L | the mutation is associated with low to medium levels of resistance to the HCV NS3-4A serine protease inhibitor telaprevir (VX-950) | Hepacivirus C |
V36M | the mutation is associated with low to medium levels of resistance to the HCV NS3-4A serine protease inhibitor telaprevir (VX-950) | Hepacivirus C |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
STAT-C | - |
Hepacivirus C | |
telaprevir | VX-950 | Hepacivirus C |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hepacivirus C | - |
genotypes 1a, 1b, and 3a | - |
Synonyms | Comment | Organism |
---|---|---|
NS3 protease | - |
Hepacivirus C |
NS3-4A serine protease | - |
Hepacivirus C |