Protein Variants | Comment | Organism |
---|---|---|
analysis | versatile system for monitoring the activity of enzyme in mammalian cells relying on coexpression of enzyme and an artificial substrate containing a reporter domain and an intracellular targeting sequence separated by an enzyme-specific cleavage site | Hepacivirus C |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-(tert-butoxycarbonyl)-D-valyl-(4S)-N-(1-carboxy-2-ethenylcyclopropyl)-4-[(7-methoxy-2-phenylquinolin-4-yl)oxy]-D-prolinamide | 50% inhibition of processing of substrate SEAP-1 at 0.00026 mM | Hepacivirus C | |
N-acetyl-L-alpha-aspartyl-L-alpha-glutamyl-b-phenyl-L-phenylalanyl-L-alpha-glutamyl-N-[1-(carboxycarbonyl)-3,3-difluoropropyl]-3-cyclohexyl-L-alaninamide | 50% inhibition of processing of substrate SEAP-1 at 0.0067 mM | Hepacivirus C |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hepacivirus C | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CD8-1 + H2O | synthetic substrate consisting of lymphocyte surface antigen CD8alpha, an enzyme cleavage site and a membrane anchor featuring an endoplasmic reticulum retention sequence | Hepacivirus C | ? | - |
? | |
SEAP-1 + H2O | synthetic substrate consisting of alkaline phosphatase, an enzyme cleavage site and a membrane anchor featuring an endoplasmic reticulum retention sequence | Hepacivirus C | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NS3-4A serine protease | - |
Hepacivirus C |