Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Asp-Glu-Leu-Ile-L-cyclohexylalanine-aminobutyryl-(Me)Ala-Ser-His-Leu | IC50: 5 mM | Hepacivirus C | |
Asp-Glu-Leu-Ile-L-cyclohexylalanine-Cys-OH | IC50: 15 nM | Hepacivirus C | |
Asp-Glu-Leu-Ile-L-cyclohexylalanine-Cys-Pro-L-cyclohexylalanine-Asp-Leu | IC50 below 0.2 nM | Hepacivirus C | |
Asp-Glu-Leu-Ile-L-cyclohexylalanine-Cys-Pro-Nle-Ser-Leu | IC50: 10 nM | Hepacivirus C | |
additional information | the effect of prime-site occupancy on the enzyme structure | Hepacivirus C |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hepacivirus C | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
serine protease NS3 | - |
Hepacivirus C |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0000002 | - |
IC50 below 0.2 nM | Hepacivirus C | Asp-Glu-Leu-Ile-L-cyclohexylalanine-Cys-Pro-L-cyclohexylalanine-Asp-Leu | |
0.00001 | - |
IC50: 10 nM | Hepacivirus C | Asp-Glu-Leu-Ile-L-cyclohexylalanine-Cys-Pro-Nle-Ser-Leu | |
0.000015 | - |
IC50: 15 nM | Hepacivirus C | Asp-Glu-Leu-Ile-L-cyclohexylalanine-Cys-OH | |
5 | - |
IC50: 5 mM | Hepacivirus C | Asp-Glu-Leu-Ile-L-cyclohexylalanine-aminobutyryl-(Me)Ala-Ser-His-Leu |