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Literature summary for 3.4.21.94 extracted from

  • Tein, K.; Kasvandik, S.; Koks, S.; Vasar, E.; Terasmaa, A.
    Prohormone convertase 2 activity is increased in the hippocampus of Wfs1 knockout mice (2015), Front. Mol. Neurosci., 8, 45 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus P21661
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hippocampus
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
proSAAS + H2O
-
Mus musculus little-LEN + ?
-
?

Synonyms

Synonyms Comment Organism
PC2
-
Mus musculus

General Information

General Information Comment Organism
physiological function in wolframin knockout mice, the activity of PC2 in hippocampus is significantly increased, while the protein levels of proPC2 and PC2 and of chaperone secretogranin are unchanged. The processing of proSAAS and proenkephalin is altered in the hippocampus of wolframin knockout mice Mus musculus