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Literature summary for 3.4.21.94 extracted from
- Regulation of prohormone convertase 2 protein expression via GPR40/FFA1 in the hypothalamus (2015), Eur. J. Pharmacol., 762, 459-463 .
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P21661 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hypothalamus | PC2 protein in the hypothalamus is colocalized with free fatty acid receptor GPR40/FFA1 | Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PCSK2 | - |
Mus musculus |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Mus musculus | intracerebroventricular injection of docosahexaenoic acid or GW9508, a free fatty acid receptor GPR40/FFA1 agonsit, significantly increases PC2 protein expression in the hypothalamus. This increase in PC2 expression is inhibited by pretreatment with GW1100, a GPR40/FFA1 antagonist. application of complete Freund's adjuvant also increases expression | up |
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Release 2023.1 (January 2023)
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