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Literature summary for 3.4.21.94 extracted from

  • Pan, H.; Che, F.Y.; Peng, B.; Steiner, D.F.; Pintar, J.E.; Fricker, L.D.
    The role of prohormone convertase-2 in hypothalamic neuropeptide processing: a quantitative neuropeptidomic study (2006), J. Neurochem., 98, 1763-1777.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information approximately one third of peptides found in wild-type mice are not detectable in PC2 knock-out mice, and another third are present at levels ranging from 25 to 75% of wild-type levels Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
hypothalamus
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Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information sequences with a Trp, Tyr and/or Pro in the P1' or P2' position, or a basic residue in the P3 position, are preferentially cleaved by PC2 Mus musculus ?
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?

Synonyms

Synonyms Comment Organism
PC2
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Mus musculus
prohormone convertase-2
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Mus musculus