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Literature summary for 3.4.21.94 extracted from

  • Tzimas, G.N.; Chevet, E.; Jenna, S.; Nguyen, D.T.; Khatib, A.M.; Marcus, V.; Zhang, Y.; Chretien, M.; Seidah, N.; Metrakos, P.
    Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases (2005), BMC Cancer, 5, 149.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens proprotein convertases play a major role in liver metastasis ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colonic cancer cell primary Homo sapiens
-
liver high expression level of PC2 in normal, unaffected liver Homo sapiens
-
liver cancer cell metastase originating from colorectal cancer, 2fold reduced expression compared to healthy liver Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information proprotein convertases play a major role in liver metastasis Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
PC2
-
Homo sapiens