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Literature summary for 3.4.21.93 extracted from

  • Tagen, M.B.; Beinfeld, M.C.
    Recombinant prohormone convertase 1 and 2 cleave purified pro cholecystokinin (CCK) and a synthetic peptide containing CCK 8 Gly Arg Arg and the carboxyl-terminal flanking peptide (2005), Peptides, 26, 2530-2535.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pro-cholecystokinin + H2O Mus musculus the substrate is only cleaved in vivo since defolding proteins ar required, in vitro the cleavage site is inaccessible for the enzyme N-terminal propeptide + C-terminal cholecystokinin 8 Gly Arg Arg peptide + remaining CCK peptide peptide product analysis ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cholecystokinin 8-containing peptide + H2O a synthetic peptide substrate containing the CCK 8 Gly Arg Arg peptide sequence, i.e. DYMGWMDF, and the cleavage site of pro-cholecystokinin for its liberation, overview Mus musculus ?
-
?
pro-cholecystokinin + H2O the substrate is only cleaved in vivo since defolding proteins ar required, in vitro the cleavage site is inaccessible for the enzyme Mus musculus N-terminal propeptide + C-terminal cholecystokinin 8 Gly Arg Arg peptide + remaining CCK peptide peptide product analysis ?
pro-cholecystokinin + H2O the substrate is only cleaved at the CKK 8 peptide in vivo since defolding proteins ar required, in vitro the cleavage site is inaccessible for the enzyme Mus musculus N-terminal propeptide + cholecystokinin 58 peptide product analysis ?

Synonyms

Synonyms Comment Organism
PC1
-
Mus musculus
prohormone convertase 1
-
Mus musculus