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Literature summary for 3.4.21.92 extracted from

  • Gottesman, S.; Clark, W.P.; de Crecy-Lagard, V.; Maurizi, M.R.
    ClpX, an alternative subunit for the ATP-dependent Clp protease of Escherichia coli. Sequence and in vivo activities (1993), J. Biol. Chem., 268, 22618-22626.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
46300
-
x * 46300, ClpX, calculation from amino acid sequence Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Escherichia coli selectivity of degradation by ClpP in vivo is determined by interaction of ClpP with different regulatory ATPase subunits ?
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
ClpX Escherichia coli

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Bacteriophage lambdaO-DNA replication protein + H2O degraded by ClpXP Escherichia coli Hydrolyzed bacteriophage lambdaO-DNA replication protein
-
?
additional information selectivity of degradation by ClpP in vivo is determined by interaction of ClpP with different regulatory ATPase subunits Escherichia coli ?
-
?

Subunits

Subunits Comment Organism
? x * 46300, ClpX, calculation from amino acid sequence Escherichia coli
More enzyme consists of two components: ClpP and ClpA or ClpX Escherichia coli
More ClpX participates with ClpP in the rapid and specific degradation of the lambda O protein Escherichia coli