KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00013 | - |
o-aminobenzoyl-ARKKSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.0006 | - |
o-aminobenzoyl-AKRKSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.0015 | - |
o-aminobenzoyl-ARRKSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.002 | - |
o-aminobenzoyl-AKRRSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.0021 | - |
o-aminobenzoyl-KRRSSKQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.0022 | - |
SSRKRRSHDVLTQ | pH 9.0, 37°C | Yellow fever virus | |
0.0025 | - |
MKTGRRGSANGKQ | pH 9.0, 37°C | Yellow fever virus | |
0.0027 | - |
KLAQRRVFHGVAQ | pH 9.0, 37°C | Yellow fever virus | |
0.005 | - |
o-aminobenzoyl-AGRKSAQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.0066 | - |
o-aminobenzoyl-AKKKSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.0073 | - |
o-aminobenzoyl-AGKRSAQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.0076 | - |
o-aminobenzoyl-AKKRSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.0085 | - |
VRGARRSGDVLWQ | pH 9.0, 37°C | Yellow fever virus | |
0.0087 | - |
o-aminobenzoyl-AGKKSAQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.0088 | - |
SAAQRRGRIGRNQ | pH 9.0, 37°C | Yellow fever virus | |
0.0096 | - |
o-aminobenzoyl-ARRRSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.012 | - |
o-aminobenzoyl-KKRSSKQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.014 | - |
o-aminobenzoyl-ARKRSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.015 | - |
FAEGRRGAAEVLQ | pH 9.0, 37°C | Yellow fever virus | |
0.02 | - |
o-aminobenzoyl-AGRRSAQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.02 | - |
RIFGRRSIPVNEQ | pH 9.0, 37°C | Yellow fever virus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
NaCl | kcat/Km values decrease by adding NaCl up to 100 mM. This results from the systematic increase in Km values with the increase in NaCl concentration in the range 1 to 10 mM | Yellow fever virus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Yellow fever virus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
FAEGRRGAAEVLQ + H2O | - |
Yellow fever virus | FAEGRR + GAAEVLQ | - |
? | |
KLAQRRVFHGVAQ + H2O | - |
Yellow fever virus | KLAQRR + VFHGVAQ | - |
? | |
MKTGRRGSANGKQ + H2O | - |
Yellow fever virus | MKTGRR + GSANGKQ | - |
? | |
o-aminobenzoyl-AGKKSAQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-AGKK + SAQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-AGKRSAQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-AGKR + SAQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-AGRKSAQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-AGRK + SAQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-AGRRSAQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-AGRR + SAQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-AKKKSQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-AKKK + SQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-AKKRSQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-AKKR + SQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-AKRKSQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-AKRK + SQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-AKRRSQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-AKRR + SQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-ARKKSQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-ARKK + SQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-ARKRSQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-ARKR + SQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-ARRKSQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-ARRK + SQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-ARRRSQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-ARRR + SQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-KKRSSKQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-KKR + SSKQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
o-aminobenzoyl-KRRSSKQ-N-(2,4-dinitrophenyl)-ethylenediamine + H2O | - |
Yellow fever virus | o-aminobenzoyl-KRR + SSKQ-N-(2,4-dinitrophenyl)-ethylenediamine | - |
? | |
RIFGRRSIPVNEQ + H2O | - |
Yellow fever virus | RIFGRR + SIPVNEQ | - |
? | |
SAAQRRGRIGRNQ + H2O | - |
Yellow fever virus | SAAQRRGRIGRNQ | - |
? | |
SSRKRRSHDVLTQ + H2O | - |
Yellow fever virus | SSRKRR + SHDVLTQ | - |
? | |
VRGARRSGDVLWQ + H2O | - |
Yellow fever virus | VRGARR + SGDVLWQ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
YFV NS2B/NS3 protease | - |
Yellow fever virus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Yellow fever virus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.001 | - |
o-aminobenzoyl-AGKKSAQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.001 | - |
FAEGRRGAAEVLQ | pH 9.0, 37°C | Yellow fever virus | |
0.002 | - |
o-aminobenzoyl-ARKKSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.003 | - |
KLAQRRVFHGVAQ | pH 9.0, 37°C | Yellow fever virus | |
0.004 | - |
o-aminobenzoyl-AKKKSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.005 | - |
o-aminobenzoyl-AGRKSAQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.005 | - |
o-aminobenzoyl-ARRKSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.005 | - |
RIFGRRSIPVNEQ | pH 9.0, 37°C | Yellow fever virus | |
0.01 | - |
o-aminobenzoyl-AGKRSAQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.012 | - |
o-aminobenzoyl-AKRKSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.012 | - |
MKTGRRGSANGKQ | pH 9.0, 37°C | Yellow fever virus | |
0.012 | - |
o-aminobenzoyl-KKRSSKQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.016 | - |
SAAQRRGRIGRNQ | pH 9.0, 37°C | Yellow fever virus | |
0.025 | - |
o-aminobenzoyl-KRRSSKQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.026 | - |
o-aminobenzoyl-AKRRSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.041 | - |
VRGARRSGDVLWQ | pH 9.0, 37°C | Yellow fever virus | |
0.06 | - |
o-aminobenzoyl-ARKRSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.061 | - |
o-aminobenzoyl-AGRRSAQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.069 | - |
SSRKRRSHDVLTQ | pH 9.0, 37°C | Yellow fever virus | |
0.097 | - |
o-aminobenzoyl-AKKRSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.12 | - |
o-aminobenzoyl-ARRRSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9.2 | - |
- |
Yellow fever virus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7 | 10.5 | enzyme retains more than 90% of its initial protease activity | Yellow fever virus |
7 | - |
Km value increases 5times when pH range is lowered from 8.5 to 7 | Yellow fever virus |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.07 | - |
FAEGRRGAAEVLQ | pH 9.0, 37°C | Yellow fever virus | |
0.11 | - |
o-aminobenzoyl-AGKKSAQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
0.25 | - |
RIFGRRSIPVNEQ | pH 9.0, 37°C | Yellow fever virus | |
0.6 | - |
o-aminobenzoyl-AKKKSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
1 | - |
o-aminobenzoyl-AGRKSAQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
1 | - |
o-aminobenzoyl-KKRSSKQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
1.1 | - |
KLAQRRVFHGVAQ | pH 9.0, 37°C | Yellow fever virus | |
1.37 | - |
o-aminobenzoyl-AGKRSAQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
1.8 | - |
SAAQRRGRIGRNQ | pH 9.0, 37°C | Yellow fever virus | |
3.04 | - |
o-aminobenzoyl-AGRRSAQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
3.33 | - |
o-aminobenzoyl-ARRKSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
4.08 | - |
o-aminobenzoyl-ARKRSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
4.8 | - |
VRGARRSGDVLWQ | pH 9.0, 37°C | Yellow fever virus | |
4.8 | - |
MKTGRRGSANGKQ | pH 9.0, 37°C | Yellow fever virus | |
11.9 | - |
o-aminobenzoyl-KRRSSKQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
12.5 | - |
o-aminobenzoyl-ARRRSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
12.8 | - |
o-aminobenzoyl-AKKRSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
13 | - |
o-aminobenzoyl-AKRRSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
18.16 | - |
o-aminobenzoyl-ARKKSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
20 | - |
o-aminobenzoyl-AKRKSQ-N-(2,4-dinitrophenyl)-ethylenediamine | pH 9.0, 37°C | Yellow fever virus | |
31.4 | - |
SSRKRRSHDVLTQ | pH 9.0, 37°C | Yellow fever virus |