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Literature summary for 3.4.21.91 extracted from

  • Chanprapaph, S.; Saparpakorn, P.; Sangma, C.; Niyomrattanakit, P.; Hannongbua, S.; Angsuthanasombat, C.; Katzenmeier, G.
    Competitive inhibition of the dengue virus NS3 serine protease by synthetic peptides representing polyprotein cleavage sites (2005), Biochem. Biophys. Res. Commun., 330, 1237-1246.
    View publication on PubMed
Search for more literature for 3.4.21.91

Inhibitors

Inhibitors Comment Organism Structure
Ac-EVKKQR-NH2
-
 Dengue virus
Ac-FAAGRK-NH2
-
 Dengue virus
Ac-GKR-NH2
-
 Dengue virus
Ac-KKR-NH2
-
 Dengue virus
Ac-KR-NH2
-
 Dengue virus
Ac-RTSKKR-NH2
-
 Dengue virus
Ac-SKKR-NH2
-
 Dengue virus
Ac-TTSTRR-NH2
-
 Dengue virus

Organism

Organism UniProt Comment Textmining
Dengue virus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Boc-Gly-L-Arg-L-Arg-7-amido-4-methylcoumarin + H2O
-
 Dengue virus ?
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0121
-
 Ac-RTSKKR-NH2 pH 9.0, 37°C Dengue virus
0.0223
-
 Ac-KKR-NH2 pH 9.0, 37°C Dengue virus
0.0259
-
 Ac-FAAGRK-NH2 pH 9.0, 37°C Dengue virus
0.046
-
 Ac-TTSTRR-NH2 pH 9.0, 37°C Dengue virus
0.0667
-
 Ac-EVKKQR-NH2 pH 9.0, 37°C Dengue virus
0.1215
-
 Ac-KR-NH2 pH 9.0, 37°C Dengue virus
0.1523
-
 Ac-GKR-NH2 pH 9.0, 37°C Dengue virus
0.1876
-
 Ac-SKKR-NH2 pH 9.0, 37°C Dengue virus