Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.91 extracted from

  • Chambers, T.J.; Hahn, C.S.; Galler, R.; Rice, C.M.
    Flavivirus genome organization, expression, and replication (1990), Annu. Rev. Microbiol., 44, 649-688.
    View publication on PubMed
Search for more literature for 3.4.21.91

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information cytoplasmic localization with membrane association Dengue virus
-
-
additional information cytoplasmic localization with membrane association Yellow fever virus
-
-
additional information cytoplasmic localization with membrane association Flavivirus sp.
-
-
additional information viral enzyme acting in cytoplasma of host cell Dengue virus
-
-
additional information viral enzyme acting in cytoplasma of host cell Yellow fever virus
-
-
additional information viral enzyme acting in cytoplasma of host cell Flavivirus sp.
-
-
additional information viral enzyme (NS3) Dengue virus
-
-
additional information viral enzyme (NS3) Yellow fever virus
-
-
additional information viral enzyme (NS3) Flavivirus sp.
-
-
additional information NS2B is membrane component of viral replication process, presumably responsible for membrane localization of NS3 Dengue virus
-
-
additional information NS2B is membrane component of viral replication process, presumably responsible for membrane localization of NS3 Yellow fever virus
-
-
additional information NS2B is membrane component of viral replication process, presumably responsible for membrane localization of NS3 Flavivirus sp.
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
68000 70000 Flavivirus sp., predicted MW of N3 protein Flavivirus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Flavivirus sp. polyproteins + H2O Flavivirus sp. involved in processing of downstream nonstructural proteins of the virus polyprotein ?
-
 ?

Organism

Organism UniProt Comment Textmining
Dengue virus
-
 i.e. DEN2
-
Flavivirus sp.
-
 JE, KUN, MVE, SLE, WN, YF and TRE
-
Yellow fever virus
-
 i.e. YF
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Dengue virus polyprotein + H2O
-
 Dengue virus Dengue virus proteins NS3 and NS5
-
 ?
Flavivirus sp. polyproteins + H2O cleavage sites consist of Lys-Arg, Arg-Lys or Arg-Arg (Dengue virus: Gln-Arg) usually followed by Gln, Ala or Ser, cleavage sites: NS2A/2B, NS2B/3, NS3/4A (not SLE virus), NS4B/5 (not SLE virus) Flavivirus sp. ?
-
 ?
Flavivirus sp. polyproteins + H2O involved in processing of downstream nonstructural proteins of the virus polyprotein Flavivirus sp. ?
-
 ?
additional information amino-terminal third of NS3 acts as serine protease on nonstructural viral proteins Dengue virus ?
-
 ?
additional information amino-terminal third of NS3 acts as serine protease on nonstructural viral proteins Yellow fever virus ?
-
 ?
additional information amino-terminal third of NS3 acts as serine protease on nonstructural viral proteins Flavivirus sp. ?
-
 ?
Yellow fever virus protein + H2O
-
 Yellow fever virus ?
-
 ?