Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.89 extracted from

  • Aynapudi, J.; El-Rami, F.; Ge, X.; Stone, V.; Zhu, B.; Kitten, T.; Xu, P.
    Involvement of signal peptidase I in Streptococcus sanguinis biofilm formation (2017), Microbiology, 163, 1306-1318 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information generation of the biofilm mutant, DELTASSA_0351, that is deficient in type I signal peptidase (SPase). Although the growth curve of the DSSA_0351 mutant shows no significant difference from that of the wild-type strain SK36, biofilm assays using both microtitre plate assay and confocal laser scanning microscopy (CLSM) confirmed a sharp reduction in biofilm formation in the mutant compared to the wild-type strain and the paralogous mutant DSSA_0849. Evaluation of the functional impact of SPase on biofilm formation, transcriptome analysis compared to wild-type, overview. The growth rates of the wild-type, DSSA_0849 and DSSA_0351 strains are not significantly different. Proteomic analysis of mutant strain DELTASSA_0351, list of transcripts that are differentially regulated in DELTASSA_0351 Streptococcus sanguinis

Organism

Organism UniProt Comment Textmining
Streptococcus sanguinis A3CKV0
-
-
Streptococcus sanguinis SK36 A3CKV0
-
-

Synonyms

Synonyms Comment Organism
SPase
-
Streptococcus sanguinis
type I signal peptidase
-
Streptococcus sanguinis

General Information

General Information Comment Organism
malfunction the biofilm mutant, DELTASSA_0351, is deficient in type I signal peptidase (SPase), phenotype, overview. Proteomic analysis of mutant strain DELTASSA_0351, list of transcripts that are differentially regulated in DELTASSA_0351 Streptococcus sanguinis
physiological function involvement of signal peptidase I in Streptococcus sanguinis biofilm formation. Streptococcus sanguinis, a Gram-positive bacterium, is one of the most abundant species of the oral microbiota and it contributes to biofilm development in the oral cavity Streptococcus sanguinis