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Literature summary for 3.4.21.83 extracted from

  • Mikhailova, A.G.; Khairullin, R.F.; Kolomijtseva, G.Y.; Rumsh, L.D.
    Oligopeptidase B from Serratia proteamaculans. III. Inhibition analysis. Specific interactions with metalloproteinase inhibitors (2012), Biochemistry (Moscow), 77, 300-306.
    View publication on PubMed
Search for more literature for 3.4.21.83

Inhibitors

Inhibitors Comment Organism Structure
bovine basic pancreatic trypsin inhibitor substrate Nalpha-benzoyl-DL-Arg-4-nitroanilide, competitive Serratia proteamaculans
m-phenanthroline substrates Nalpha-benzoyl-DL-Arg-4-nitroanilide, acetyl-Leu-Leu-Arg-4-nitroanilide, anticompetitive Serratia proteamaculans
o-phenanthroline substrates Nalpha-benzoyl-DL-Arg-4-nitroanilide, acetyl-Leu-Leu-Arg-4-nitroanilide, anticompetitive Serratia proteamaculans
ZnCl2 substrate Nalpha-benzoyl-DL-Arg-4-nitroanilide, noncompetitive Serratia proteamaculans

Organism

Organism UniProt Comment Textmining
Serratia proteamaculans B3VI58
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-Leu-Leu-Arg-4-nitroanilide + H2O
-
 Serratia proteamaculans acetyl-Leu-Leu-Arg + 4-nitroaniline
-
 ?
Nalpha-benzoyl-DL-Arg-4-nitroanilide + H2O
-
 Serratia proteamaculans Nalpha-benzoyl-DL-Arg + 4-nitroaniline
-
 ?

Synonyms

Synonyms Comment Organism
OpdB
-
 Serratia proteamaculans

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000035
-
 bovine basic pancreatic trypsin inhibitor substrate Nalpha-benzoyl-DL-Arg-4-nitroanilide, pH 8.0, 25°C Serratia proteamaculans
0.00735
-
 bovine basic pancreatic trypsin inhibitor substrate Nalpha-benzoyl-DL-Arg-4-nitroanilide, presence of 50 mM Ca2+, pH 8.0, 25°C Serratia proteamaculans
0.0244
-
 ZnCl2 substrate Nalpha-benzoyl-DL-Arg-4-nitroanilide, pH 8.0, 25°C Serratia proteamaculans
0.31
-
 m-phenanthroline substrate Nalpha-benzoyl-DL-Arg-4-nitroanilide, pH 8.0, 25°C Serratia proteamaculans
0.44
-
 m-phenanthroline substrate acetyl-Leu-Leu-Arg-4-nitroanilide, pH 8.0, 25°C Serratia proteamaculans
0.82
-
 o-phenanthroline substrate acetyl-Leu-Leu-Arg-4-nitroanilide, pH 8.0, 25°C Serratia proteamaculans
1.59
-
 o-phenanthroline substrate Nalpha-benzoyl-DL-Arg-4-nitroanilide, pH 8.0, 25°C Serratia proteamaculans