Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | design of inhibitors based on turkey ovomucoid third domain OMTKY3. Variant 13D14Y15G18I19K21-OMTKY3 displays a Gly residue in position P1 and represents the strongest possible inhibitor due to consensus contacts to the enzyme. Inhibitor has significantly higher DeltaGo value for protease B than that for protease A and inhibits protease B 10 times more strongly than protease A; OMTKY3 inhibitor variant screening, overview | Streptomyces griseus | |
protein inhibitor S13D14Y15-OMTKY3 | a OMTKY3 mutant variant, recombinantly produced in Escherichia coli strain RV308 and purified, strong inhibition, overview | Streptomyces griseus | |
protein inhibitor S13D14Y15G18I19K21-OMTKY3 | a OMTKY3 mutant variant, recombinantly produced in Escherichia coli strain RV308 and purified, strong inhibition, overview. S13D14Y15G18I19K21 OMTKY3 inhibits Streptomyces griseus protease B 10times more strongly than Streptomyces griseus protease A, EC 3.4.21.80 | Streptomyces griseus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces griseus | - |
- |
- |
Streptomyces griseus | P00777 | - |
- |
Purification (Comment) | Organism |
---|---|
further purification of a commercial preparation | Streptomyces griseus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | requires further purification | Streptomyces griseus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-Ala-Ala-Pro-X-4-nitroanilide + H2O | - |
Streptomyces griseus | ? | - |
? | |
succinyl-Ala-Ala-Pro-X-7-amido-4-methylcoumarin + H2O | - |
Streptomyces griseus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SGPB | - |
Streptomyces griseus |
SprB | - |
Streptomyces griseus |
Streptomyces griseus protease B | - |
Streptomyces griseus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | 8.3 | assay at | Streptomyces griseus |