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Literature summary for 3.4.21.79 extracted from

  • Hodge, S.; Hodge, G.; Ahern, J.; Liew, C.L.; Hopkins, P.; Chambers, D.C.; Reynolds, P.N.; Holmes, M.
    Increased levels of T cell granzyme b in bronchiolitis obliterans syndrome are not suppressed adequately by current immunosuppressive regimens (2009), Clin. Exp. Immunol., 158, 230-236.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood granzyme B expression is increased in lung transplant patients Homo sapiens
-
bronchoalveolar lavage granzyme B expression is increased in lung transplant patients Homo sapiens
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additional information large airway brushing: granzyme B expression is increased in lung transplant patients Homo sapiens
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Synonyms

Synonyms Comment Organism
granzyme B
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens expression of granzyme B is higher in patients with Bronchiolitis obliterans syndrome than in patients with acute lung transplant rejection up
Homo sapiens in blood, bronchoalveolar lavage (BAL) and large airway brushing expression of granzyme B is significantly increased in lung transplant patients up

General Information

General Information Comment Organism
physiological function increased T cell granzyme b production may contribute to Bronchiolitis obliterans syndrome pathogenesis and is not curtailed by current immunosuppressants Homo sapiens