Inhibitors | Comment | Organism | Structure |
---|---|---|---|
serpin inhibitor PI-9 | granzyme B specific serpin inhibitor, complexation of enzyme with inhibitor prevents recognition by receptor importin beta and eliminates requirement of importin alpha for nuclear import | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | for nuclear import, receptor importin alpha is required, while receptor importin beta inhibits import | Homo sapiens | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Subunits | Comment | Organism |
---|---|---|
More | enzyme interacts with either of the nuclear import receptor family members importin alpha and beta, but in addition exogenous cytosol is required for nuclear import of enzyme | Homo sapiens |