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Literature summary for 3.4.21.79 extracted from
- The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity (2000), Nat. Struct. Biol., 7, 762-765.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| crystals by hanging drop vapor diffusion, in complex with a macromolecular inhibitor ecotin, space group P2(1), a = 56.64 A, b = 154.6 A, c = 57.24 A | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ecotin[81-84IEPD] | - |
Rattus norvegicus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | mediates cell death by cytotoxic lymphocytes | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
rat | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | processing enzyme, requires extended peptide substrates containing an Asp residue | Rattus norvegicus | ? | - |
? | |
| additional information | mediates cell death by cytotoxic lymphocytes | Rattus norvegicus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| rat grB[N66Q] | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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