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Literature summary for 3.4.21.79 extracted from

  • Andrade, F.; Casciola-Rosen, L.A.; Rosen, A.
    A novel domain in adenovirus L4-100K is required for stable binding and efficient inhibition of human granzyme B: possible interaction with a species-specific exosite (2003), Mol. Cell. Biol., 23, 6315-6326.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
cloned and expressed in Pichia pastoris Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
100K assembly protein of human adenovirus type 5 potent and specific inhibitor Homo sapiens
additional information no inhibition with 100K assembly protein of human adenovirus type 5 Mus musculus
additional information no inhibition with 100K assembly protein of human adenovirus type 5 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens protects the organism against intracellular infections and cellular transformation, implicated in the generation of tissue damage in a variety of chronic conditions, including autoimmunity and transplant rejection ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-
Mus musculus
-
 mouse
-
Rattus norvegicus
-
 rat
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information protects the organism against intracellular infections and cellular transformation, implicated in the generation of tissue damage in a variety of chronic conditions, including autoimmunity and transplant rejection Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
GrB
-
 Homo sapiens
GrB
-
 Rattus norvegicus