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Literature summary for 3.4.21.79 extracted from
- Processing and activation of CMH-1 by granzyme B (1996), J. Biol. Chem., 271, 10816-10820.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | plays an essential role in cytotoxic T-lymphocyte-mediated cell killing | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | plays an essential role in cytotoxic T-lymphocyte-mediated cell killing | Homo sapiens | ? | - |
? | |
| Protease CMH-1 + H2O | a close homologue of CPP32, granzyme B specifically cleaves at Asp198-Ser199 between the p20 and p12 and activates the cysteine protease | Homo sapiens | ? | - |
? | |
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