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Literature summary for 3.4.21.78 extracted from

  • Chaves-Pozo, E.; Valero, Y.; Lozano, M.T.; Rodriguez-Cerezo, P.; Miao, L.; Campo, V.; Esteban, M.A.; Cuesta, A.
    Fish granzyme A shows a greater role than granzyme B in fish innate cell-mediated cytotoxicity (2019), Front. Immunol., 10, 2579.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Dicentrarchus labrax A0A076YF64
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Sparus aurata A0A5C2IE33
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-

Source Tissue

Source Tissue Comment Organism Textmining
leukocyte head-kidney leukocyte. Transcription of gzma is significantly up-regulated in seabream head-kidney leukocytes against mock-infected target cells compared to naive head-kidney leukocytes alone, and this up-regulation is even higher when the targets are infected with nodavirus Sparus aurata
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leukocyte head-kidney leukocyte Dicentrarchus labrax
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Synonyms

Synonyms Comment Organism
Gzma
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Sparus aurata
Gzma
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Dicentrarchus labrax

Expression

Organism Comment Expression
Sparus aurata transcription of gzma is significantly up-regulated in seabream head-kidney leukocytes against mock-infected target cells compared to naive head-kidney leukocytes alone, and this up-regulation is even higher when the targets are infected with nodavirus up
Dicentrarchus labrax the expression of gzma gene in head-kidney leukocytes is significantly up-regulated against E-11 target cells compared to naive head-kidney leukocytes. mRNA levels of gzma is further increased during cell-mediated cytotoxicity assays against nodavirus-target cells up

General Information

General Information Comment Organism
physiological function high functional activity of GzmA in the innate cell-mediated cytotoxicity Sparus aurata
physiological function high functional activity of GzmA in the innate cell-mediated cytotoxicity Dicentrarchus labrax