Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P11032 | granzyme A precursor; interleukin 4-deficient BALB/c mice and wild-type BALB/c controls | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lymphocyte | lysates of CD8+ tumor associated lymphocytes, Interleukin 4-deficient mice | Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
enzymatic activity of granzyme A measured in lysates of CD8+ tumor associated lymphocytes of interleukin 4-deficient and wild-type BALB/c mice, significant increase in the fraction of CD8+ tumor associated T-cells expressing granzyme A identified, in interleukin 4-deficient mice, the frequency of CD8+ tumor associated lymphocytes expressing granzyme A significantly increases between days 8 and 14, expression at background levels by day 21, increase in the percentage of CD8+ tumor associated lymphocytes expressing granzyme A less pronounced in wild-type mice | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
H-D-Pro-Phe-Arg p-nitroanilide + H2O | i.e. S2302, measurement of enzymatic activity of granzyme A activity in lysates of CD8+ TAL | Mus musculus | H-D-Pro-Phe-Arg + p-nitroaniline | - |
? | |
N-acetyl-Ile-Glu-Pro-Asp p-nitroanilide + H2O | measurement of enzymatic activity of granzyme A activity in lysates of CD8+ TAL | Mus musculus | N-acetyl-Ile-Glu-Pro-Asp + p-nitroaniline | - |
? |