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Literature summary for 3.4.21.78 extracted from

  • Vernooy, J.H.; Moeller, G.M.; van Suylen, R.J.; van Spijk, M.P.; Cloots, R.H.; Hoet, P.H.; Pennings, H.J.; Wouters, E.F.
    Increased granzyme A expression in type II pneumocytes of patients with severe chronic obstructive pulmonary disease (2007), Am. J. Respir. Crit. Care Med., 175, 464-472.
    View publication on PubMed
Search for more literature for 3.4.21.78

Application

Application Comment Organism
medicine involvement of granzyme A in development of chronic obstructive pulmonary disease (COPD) shown, increased expression of granzyme A in type II pneumocytes indicated Homo sapiens
medicine involvement of granzyme A in development of chronic obstructive pulmonary disease shown Homo sapiens
medicine involvement of granzyme A in development of chronic obstructive pulmonary disease shown, increased expression of granzyme A in type II pneumocytes Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P12544
-
-

Source Tissue

Source Tissue Comment Organism Textmining
alveolar cell type II primary type II pneumocytes and type II pneumocyte, from patients with chronic obstructive pulmonary disease, enriched by Laser capture microdissection (LCM) Homo sapiens
-
alveolar macrophage peripheral lung tissue from patients with chronic obstructive pulmonary disease, enriched by Laser capture microdissection (LCM) Homo sapiens
-
natural killer cell CD57+ natural killer cells Homo sapiens
-
T-lymphocyte CD8+ cytotoxic T lymphocytes Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 RNA accumulation and immunohistochemistry of granzyme A investigated Homo sapiens
additional information
-
 RNA accumulation and immunohistochemistry of granzyme A investigated, application of Laser capture dissection (LCM) to analyse accumulation of granzyme A in specific lung tissue Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information study to analyze importance of granzyme A in development of chronic obstructive pulmonary disease (COPD) Homo sapiens ?
-
 ?
additional information study to analyze the role of granzyme A in development of chronic obstructive pulmonary disease (COPD) Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
GrA
-
 Homo sapiens