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Literature summary for 3.4.21.78 extracted from

  • Hink-Schauer, C.; Estebanez-Perpina, E.; Kurschus, F.C.; Bode, W.; Jenne, D.E.
    Crystal structure of the apoptosis-inducing human granzyme A dimer (2003), Nat. Struct. Biol., 10, 535-540.
    View publication on PubMed
Search for more literature for 3.4.21.78

Cloned(Commentary)

Cloned (Comment) Organism
bone marrow cDNA used to amplify Gzma by PCR Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
triclinic space group P1, a = 49.48 A, b = 94.55 A, c = 94.87 A Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasmic vesicle
-
 Homo sapiens 31410
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-alpha-benzyloxycarbonyl-Arg-SBzl + H2O
-
 Homo sapiens ?
-
 ?
Nalpha-benzyloxycarbonyl-Lys-SBzl + H2O
-
 Homo sapiens Nalpha-benzyloxycarbonyl-Lys + phenylmethanethiol
-
 ?
PHAPII + H2O
-
 Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
dimer only granzyme that forms a disulfide-linked homodimer Homo sapiens

Synonyms

Synonyms Comment Organism
Gzma
-
 Homo sapiens