Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.78 extracted from

  • Bell, J.K.; Goetz, D.H.; Mahrus, S.; Harris, J.L.; Fletterick, R.J.; Craik, C.S.
    The oligomeric structure of human granzyme A is a determinant of its extended substrate specificity (2003), Nat. Struct. Biol., 10, 527-534.
    View publication on PubMed
Search for more literature for 3.4.21.78

Cloned(Commentary)

Cloned (Comment) Organism
cDNA subcloned into the yeast vector pPICzalphaA and heterologously expressed in Pichia pastoris Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Homo sapiens

Protein Variants

Protein Variants Comment Organism
N153Q molecular replacement Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
additional information ecotin has no effect Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens cell death-inducing serine protease ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information cell death-inducing serine protease Homo sapiens ?
-
 ?
PSSCL + H2O
-
 Homo sapiens Pro-Ser + Ser-Lys-Lys
-
 ?

Subunits

Subunits Comment Organism
dimer only granzyme that forms a disulfide-linked homodimer Homo sapiens
oligomer
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
Gzma
-
 Homo sapiens