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Literature summary for 3.4.21.78 extracted from

  • Simon, M.M.; Hoschutzky, H.; Fruth, U.; Simon, H.G.; Kramer, M.D.
    Purification and characterization of a T cell specific serine proteinase (TSP-1) from cloned cytolytic T lymphocytes (1986), EMBO J., 5, 3267-3274.
    View publication on PubMed
Search for more literature for 3.4.21.78

Cloned(Commentary)

Cloned (Comment) Organism
-
 Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
3-aminobenzamidine
-
 Mus musculus
4-aminobenzamidine
-
 Mus musculus
Aprotinin
-
 Mus musculus
diisopropyl fluorophosphate
-
 Mus musculus
leupeptin
-
 Mus musculus
additional information not: inhibitors of either thiol-, metallo- or carboxyl-proteinases Mus musculus
phenylmethanesulfonyl fluoride
-
 Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 x * 60000, mouse, SDS-PAGE under nonreducing condition, x * 30000, SDS-PAGE under reducing condition, mouse Mus musculus
60000
-
 x * 60000, mouse, SDS-PAGE under nonreducing condition, x * 30000, SDS-PAGE under reducing condition, mouse Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus TSP-1 has the capacity to stimulate B lymphocytes for proliferation in the absence of antigen ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
T-lymphocyte
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-Pro-Phe-Arg 4-nitroanilide + H2O low or no activity against peptide synthetic substrates carrying other amino acid sequences at position P2, P3 adjacent to L-arginine or against substrates in which amino acids other than L-arginine are bound to the nitroanilide group Mus musculus D-Pro-Phe-Arg + 4-nitroaniline
-
 ?
additional information TSP-1 has the capacity to stimulate B lymphocytes for proliferation in the absence of antigen Mus musculus ?
-
 ?

Subunits

Subunits Comment Organism
? x * 60000, mouse, SDS-PAGE under nonreducing condition, x * 30000, SDS-PAGE under reducing condition, mouse Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8 8.5 D-Pro-Phe-Arg 4-nitroanilide Mus musculus