Literature summary for 3.4.21.77 extracted from

Parracino, A.; Neves-Petersen, M.T.; di Gennaro, A.K.; Pettersson, K.; Loevgren, T.; Petersen, S.B.
Arraying prostate specific antigen PSA and Fab anti-PSA using light-assisted molecular immobilization technology (2010), Protein Sci., 19, 1751-1759.

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Application

Application	Comment	Organism
analysis	development of PSA and Fab anti-PSA biosensor arrays using UV light-assisted molecular immobilization LAMI, aiming at the detection and quantification of PSA, as a cancer marker. The technology involves formation of free, reactive thiol groups upon UV excitation of protein aromatic residues located in spatial proximity of disulfide bridges, conserved in both PSA and Fab molecules. The thiol groups bind onto thiol reactive surfaces leading to oriented covalent protein immobilization. LAMI technology is successful in immobilizing biomedically relevant molecules while preserving their activity	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
commercial preparation	-	Homo sapiens	-

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Release 2023.1 (January 2023)