Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli M15(pREP4) cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Aprotinin | efficient inhibition | Homo sapiens | |
Bovine pancreatic trypsin inhibitor | efficient inhibition | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
nickel-nitrilotriacetic acid-Sepharose column chromatography and benzamidine-Sepharose column chromatography | Homo sapiens |
Renatured (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
prostate gland | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | slightly prefers Met over Nle and Ala at the P1 position of the fluorogenic substrates but also tolerates Leu, Tyr, Phe, and the basic residues Arg and Lys, whereas Asp and Thr are not accepted at all, In the S2 subsite Leu is slightly preferred over Ala, Gln, Met, and Tyr | Homo sapiens | ? | - |
? | |
succinyl-AAPF-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | succinyl-AAPF + 7-amino-4-methylcoumarin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
hK3/PSA | exhibits a chymotrypsin-like specificity preferring large hydrophobic or polar residues at the P1 position | Homo sapiens |
prostate-specific antigen | - |
Homo sapiens |
PSA | - |
Homo sapiens |