Any feedback?
Literature summary for 3.4.21.76 extracted from
- Differences in the substrate binding sites of murine and human proteinase 3 and neutrophil elastase (2007), FEBS Lett., 581, 5685-5690.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DRDAVDRDID + H2O | - |
Mus musculus | ? | - |
? |  |
| DVARVKDRQEG + H2O | - |
Mus musculus | ? | - |
? | |
| GDVAVYEEN + H2O | - |
Mus musculus | ? | - |
? | |
| additional information | in mouse PR3 binding sites S6, S5, S1' and S3' are clearly polar, S2' is pretty polar, while S4, S3, S1, S4' are rather hydrophobic. VADVKDR does not interact properly with mouse PR3 | Mus musculus | ? | - |
? | |
| RDVARCRDRQEG + H2O | - |
Mus musculus | ? | - |
? | |
| RDVARCRDRQQG + H2O | - |
Mus musculus | ? | - |
? | |
| VADVKDR + H2O | highly specific of and efficiently cleaved by human PR3 | Homo sapiens | ? | - |
? | |
| VARVRDR + H2O | - |
Mus musculus | ? | - |
? | |
| VARVRDR + H2O | - |
Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PR3 | - |
Mus musculus |
| PR3 | - |
Homo sapiens |
| PR3 | - |
Rattus norvegicus |
| proteinase 3 | - |
Mus musculus |
| proteinase 3 | - |
Homo sapiens |
| proteinase 3 | - |
Rattus norvegicus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
