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Literature summary for 3.4.21.76 extracted from

  • Hirche, T.O.; Crouch, E.C.; Espinola, M.; Brokelman, T.J.; Mecham, R.P.; DeSilva, N.; Cooley, J.; Remold-O'Donnell, E.; Belaaouaj, A.
    Neutrophil serine proteinases inactivate surfactant protein D by cleaving within a conserved subregion of the carbohydrate recognition domain (2004), J. Biol. Chem., 279, 27688-27698.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
4-(2-aminoethyl)benzenesulfonyl fluoride
-
Homo sapiens
diisopropyl fluorophosphate
-
Homo sapiens
phenylmethylsulfonyl fluoride
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P24158
-
-
Mus musculus Q61096
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
Homo sapiens
-
lung
-
Mus musculus
-
neutrophil
-
Homo sapiens
-
neutrophil
-
Mus musculus
-
sputum
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-Boc-Ala-o-nitrophenol + H2O 37°C, pH 7.4 Homo sapiens ?
-
?
surfactant protein D + H2O
-
Mus musculus ? a fragment of about 35000 Da ?
surfactant protein D + H2O 37°C, pH 7.4 Homo sapiens ? a fragment of about 35000 Da ?

Synonyms

Synonyms Comment Organism
Proteinase-3
-
Homo sapiens
Proteinase-3
-
Mus musculus