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Literature summary for 3.4.21.75 extracted from

  • Tay, F.P.; Huang, M.; Wang, L.; Yamada, Y.; Liu, D.X.
    Characterization of cellular furin content as a potential factor determining the susceptibility of cultured human and animal cells to coronavirus infectious bronchitis virus infection (2012), Virology, 433, 421-430.
    View publication on PubMed
Search for more literature for 3.4.21.75

Protein Variants

Protein Variants Comment Organism
additional information enhancement of productive IBV infection by knockin of furin in A-549 cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
IBV spike protein + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens P09958
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEP-3B cell
-
 Homo sapiens
-
Hep-G2 cell
-
 Homo sapiens
-
Huh-7 cell
-
 Homo sapiens
-
additional information cellular furin abundance in five human cell lines is shown to be strongly correlated with productive infectious bronchitis virus, IBV, infection, cells expressing furin, overview Homo sapiens
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NCI-H1299 cell
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 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
IBV spike protein + H2O
-
 Homo sapiens ?
-
 ?

General Information

General Information Comment Organism
malfunction ablation of productive infectious bronchitis virus, IBV, infection by knockdown of furin expression in H1299 cells Homo sapiens
metabolism cellular furin content might be a potential factor determining the susceptibility of cultured human and animal cells to coronavirus infectious bronchitis virus infection Homo sapiens