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Literature summary for 3.4.21.75 extracted from
- Inter-alpha-inhibitor proteins are endogenous furin inhibitors and provide protection against experimental anthrax intoxication (2005), Infect. Immun., 73, 5101-5105.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| inter-alpha-inhibitor protein IalphaIp | blocks furin activity in vitro and provides significant protection against cytotoxocity for murine peritoneal macrophages exposed to up to 500 ng/ml anthrax lethal toxin | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-aminobenzoyl-Arg-Val-Lys-Arg-Gly-Leu-Ala-Tyr(NO2)-Asp + H2O | - |
Homo sapiens | ? | - |
? |  |
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Release 2023.1 (January 2023)
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