Literature summary for 3.4.21.75 extracted from

Shennan, K.I.J.; Smeekens, S.P.; Steiner, D.F.; Docherty, K.
Characterization of PC2, a mammalian Kex2 homologue, following expression of the cDNA in microinjected Xenopus oocytes (1991), FEBS Lett., 284, 277-280.

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Organism

Organism	UniProt	Comment	Textmining
eukaryota	-	at least 3 related enzymes are recognized in mammals: PC2	-

Synonyms

Synonyms	Comment	Organism
More	one of a group of subtilisin homologues structurally and functionally similar to kexin	eukaryota
More	at least 3 related enzymes are recognized in mammals: PC2, PC3, identical with PC1and PC4, which have somewhat different specificities, the integral membrane protein furin may be of ancient origin, possibly ancestral to the secretory granule processing enzymes lacking transmembrane domains, such as PC2 and PC3	eukaryota

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Release 2023.1 (January 2023)