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Literature summary for 3.4.21.72 extracted from

  • Murphy, T.; Lesse, A.; Kirkham, C.; Zhong, H.; Sethi, S.; Munson Jr., R.
    A clonal group of nontypeable Haemophilus influenzae with two IgA proteases is adapted to infection in chronic obstructive pulmonary disease (2011), PLoS ONE, 6, e25923.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
igaB, COPD strains, DNA sequence determination and analysis, sequence comparisons and relation to strain 11P6H, clonal relationship among the strains, overview Haemophilus influenzae

Organism

Organism UniProt Comment Textmining
Haemophilus influenzae
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nontypeable Haemophilus influenzae strains, COPD strains, genes igaA and igaB
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Synonyms

Synonyms Comment Organism
IgA protease
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Haemophilus influenzae

General Information

General Information Comment Organism
evolution Haemophilus influenzae has likely acquired igaB from Neisseria meningitidis, the acquisition is accompanied by a about 20 kb genomic inversion that is present only in strains that have igaB, overview Haemophilus influenzae
physiological function the clonally related group of strains of nontypeable Haemophilus influenzae that has two IgA1 protease genes, iga and igaB, is adapted for colonization and infection in chronic obstructive pulmonary disease, COPD Haemophilus influenzae