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Literature summary for 3.4.21.72 extracted from

  • Mortensen, S.B.; Kilian, M.
    Purification and characterization of an immunoglobulin A1 protease from Bacteroides melaninogenicus (1984), Infect. Immun., 45, 550-557.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.72

Activating Compound

Activating Compound Comment Organism Structure
additional information active only under reducing conditions Prevotella melaninogenica

Inhibitors

Inhibitors Comment Organism Structure
Traditional protease inhibitors
-
 Prevotella melaninogenica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0034
-
 IgA
-
 Prevotella melaninogenica

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
62000
-
 Bacteroides melaninogenicus Prevotella melaninogenica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
immunoglobulin A + H2O Prevotella melaninogenica
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Prevotella melaninogenica
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Prevotella melaninogenica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
IgA + H2O
-
 Prevotella melaninogenica ?
-
 ?
Immunoglobulin A + H2O cleaves a Pro-Ser bond in the hinge region of the alpha1 chain between residues 223 and 224 Prevotella melaninogenica immunoglobulin Fabalpha + immunoglobulin Fc
-
 ?
Immunoglobulin A + H2O specific for human immunoglobulin IgA1 Prevotella melaninogenica immunoglobulin Fabalpha + immunoglobulin Fc
-
 ?
immunoglobulin A + H2O
-
 Prevotella melaninogenica ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
additional information
-
 pI: 5.0 Prevotella melaninogenica
5
-
-
 Prevotella melaninogenica