Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.7 extracted from

  • Koch, T.K.; Reuter, M.; Barthel, D.; Boehm, S.; van den Elsen, J.; Kraiczy, P.; Zipfel, P.F.; Skerka, C.
    Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b (2012), PLoS ONE, 7, e47638.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.7

Activating Compound

Activating Compound Comment Organism Structure
Efb protein plasminogen bound to Efb protein is converted to plasmin Homo sapiens
Sbi protein plasminogen bound to Sbi protein is converted to plasmin Homo sapiens
urokinase-type plasminogen activator
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
92000
-
 x * 92000, plasminogen, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
complement component C3 + H2O Homo sapiens
-
 complement component C3a + ?
-
 ?
complement component C3a + H2O Homo sapiens
-
 ?
-
 ?
complement component C3b + H2O Homo sapiens the enzyme inactivates the C3b molecule for complement C3b amplification ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C3 + H2O
-
 Homo sapiens complement component C3a + ?
-
 ?
complement component C3a + H2O
-
 Homo sapiens ?
-
 ?
complement component C3b + H2O the enzyme inactivates the C3b molecule for complement C3b amplification Homo sapiens ?
-
 ?
D-Val-L-Leu-L-Lys-4-nitroanilide + H2O i.e. S-2251 Homo sapiens D-Val-L-Leu-L-Lys + 4-nitroaniline
-
 ?

Subunits

Subunits Comment Organism
? x * 92000, plasminogen, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
plasminogen pre-enzyme Homo sapiens