Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Nalpha-[[trans-4-(aminomethyl)cyclohexyl]carbonyl]-N-hexyl-O-(pyridin-4-ylmethyl)-L-tyrosinamide | binding mode | Homo sapiens | |
[4-[(N-[[trans-4-(aminomethyl)cyclohexyl]carbonyl]-L-phenylalanyl)amino]phenyl]acetic acid | binding mode | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.02 | - |
D-Ile-Phe-Lys | pH and temperature not specified in the publication | Homo sapiens | |
0.33 | - |
L-Ile-Phe-Lys | pH and temperature not specified in the publication | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | subsite interactions of plasmin with substrates and inhibitors through computational docking analysis using the structure with PDB ID 1BML for plasmin in complex with streptokinase and no ligand molecules, molecular dynamic simulation of plasmin, overview. D/L-Ile-Phe-Lys substrate-binding modes | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-Ile-Phe-Lys + H2O | - |
Homo sapiens | ? | - |
? | |
L-Ile-Phe-Lys + H2O | - |
Homo sapiens | ? | - |
? | |
additional information | subsite interactions of plasmin with substrates and inhibitors through computational docking analysis using the structure with PDB ID 1BML for plasmin in complex with streptokinase and no ligand molecules, molecular dynamic simulation of plasmin, overview. D/L-Ile-Phe-Lys substrate-binding modes | Homo sapiens | ? | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00053 | - |
pH and temperature not specified in the publication | Homo sapiens | Nalpha-[[trans-4-(aminomethyl)cyclohexyl]carbonyl]-N-hexyl-O-(pyridin-4-ylmethyl)-L-tyrosinamide | |
0.65 | - |
pH and temperature not specified in the publication | Homo sapiens | [4-[(N-[[trans-4-(aminomethyl)cyclohexyl]carbonyl]-L-phenylalanyl)amino]phenyl]acetic acid |