Any feedback?
Literature summary for 3.4.21.7 extracted from
- Plasminogen activator inhibitor-1 regulates integrin alphavbeta3 expression and autocrine transforming growth factor beta signaling (2009), J. Biol. Chem., 284, 20708-20717.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Aprotinin | - |
Mus musculus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fibroblast | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| plasmin | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | in plasminogen activator inhibotr-1 knock-out mouse embryonic fibroblasts plasmin activity. Unregulated plasmin activity is only partially responsible for TGF-beta activation as evidenced by a mere 25% reduction in TGF-beta activity when plasmin is inhibited | Mus musculus |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
