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Literature summary for 3.4.21.7 extracted from

  • Koizumi, M.; Momoeda, M.; Hiroi, H.; Nakazawa, F.; Nakae, H.; Ohno, T.; Yano, T.; Taketani, Y.
    Inhibition of proteases involved in embryo implantation by cholesterol sulfate (2010), Hum. Reprod., 25, 192-197.
    View publication on PubMed
Search for more literature for 3.4.21.7

Inhibitors

Inhibitors Comment Organism Structure
Cholesterol sulfate reduces plasmin activity in a dose-dependent manner Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endometrial stromal cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Boc-Val-Leu-Lys-4-methylcoumaryl-7-amide + H2O
-
 Homo sapiens Boc-Val-Leu-Lys + 7-amino-4-methylcoumarin
-
 ?

Synonyms

Synonyms Comment Organism
plasmin
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 assay at Homo sapiens

General Information

General Information Comment Organism
physiological function Western blot analysis of the endometrial stromal cell culture media reveals that cholesterol sulfate inhibits the conversion by plasmin of matrix metalloproteinase-3 from the precursor form to the active form Homo sapiens